Shakira will join Blake Shelton on the 49th Annual ACM Awards to perform their duet, "Medicine." The song appears on Shakira's new, self-titled album. Look for George Strait to make a major announcement about the ACM's upcoming 50th anniversary show during this year's ACM Awards, too.
Blake Shelton co-hosts the ACM Awards with Luke Bryan this Sunday night at 8 p.m. ET on CBS.
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